Either you have JavaScript disabled or your browser does not support Javascript . To work properly, this page requires JavaScript to be enabled.
How to enable JavaScript in your browser?

Vutrisiran - Alnylam Pharmaceuticals

Next Previous
Drug Profile

Vutrisiran - Alnylam Pharmaceuticals

Alternative Names: ALN-65492; ALN-TTRsc02; AMVUTTRA

Latest Information Update: 03 Sep 2025

Price :
$50 *
Note:
  • Adis is an information provider. We do not sell or distribute actual drugs.
  • Final gross price and currency may vary according to local VAT and billing address.
  • Your purchase entitles you to full access to the information contained in our drug profile at the time of purchase.
  • A link to download a PDF version of the drug profile will be included in your email receipt.

At a glance

  • Originator Alnylam Pharmaceuticals
  • Class Amides; Amino sugars; Drug conjugates; Small interfering RNA
  • Mechanism of Action Prealbumin expression inhibitors; RNA interference
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Transthyretin-related hereditary amyloidosis
  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Transthyretin-related hereditary amyloidosis

Most Recent Events

  • 31 Aug 2025 Adverse events and efficacy data from the phase-III HELIOS-B trial and it's open-label extension in Transthyretin-related hereditary amyloidosis released by Alnylam Pharmaceuticals
  • 29 Aug 2025 Efficacy data from the phase-III HELIOS-B trial in Transthyretin-related hereditary amyloidosis presented at the Annual Congress of the European Society of Cardiology together with World Congress of Cardiology (ESC-Card-WCC-2025)
  • 11 Aug 2025 Registered for Transthyretin-related hereditary amyloidosis in United Arab Emirates (SC)

You need to be a logged in or subscribed to view this content

Request demo (opens in a new window)
If your organization or you do not have a subscription, try one of the following: If your organization has a subscription, there are several access options, even while working remotely:
  • Working within your organization’s network
  • with username/password or try to via your institution
  • Persisted access using your organization’s identifier stored in your user browser for 90 days
Back to top