Pentosan polysulfate - Paradigm Biopharma

Drug Profile

Pentosan polysulfate - Paradigm Biopharma

Alternative Names: Pentosan polysulfate sodium - Paradigm Biopharma; PPS - Paradigm Biopharma; Rhinosul; ZILOSUL

Latest Information Update: 22 Dec 2017

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At a glance

  • Originator Glycan Biosciences; Griffith University
  • Developer Griffith University; Paradigm Biopharma
  • Class Analgesics; Anti-inflammatories; Anticoagulants; Antihyperlipidaemics; Antiretrovirals; Antithrombotics; Antivirals; Glycosaminoglycans; Polymers; Polysaccharides; Small molecules; Sulfuric acids
  • Mechanism of Action Cell membrane permeability inhibitors; Enzyme inhibitors; Non-nucleoside reverse transcriptase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity No

Highest Development Phases

  • Phase II Pain; Ross River virus infections; Seasonal allergic rhinitis
  • Phase I/II Oedema
  • Phase I Allergic rhinitis
  • Preclinical Allergic asthma; Chikungunya virus infections
  • Research Chronic obstructive pulmonary disease

Most Recent Events

  • 27 Oct 2017 Phase-II clinical trials in Pain in Australia (SC) (ACTRN12617001311347)
  • 18 Sep 2017 Paradigm Biopharmaceuticals plans the PARA005 phase II trial for Pain in Australia (ACTRN12617001311347 )
  • 20 Jul 2017 Phase-II clinical trials in Ross River virus infections in Australia (SC) (ACTRN12617000893303)
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