Drug Profile
Nivatrotamab - Y-mAbs Therapeutics
Alternative Names: Hu3F8 bispecific antibody - Y-mAbs Therapeutics; Hu3F8-BsAb (GD2xCD3); huGD2-BsAbLatest Information Update: 21 Jul 2022
Price :
$50
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At a glance
- Originator Memorial Sloan-Kettering Cancer Center
- Developer Memorial Sloan-Kettering Cancer Center; Y-mAbs Therapeutics
- Class Antineoplastics; Bispecific antibodies; Immunotherapies
- Mechanism of Action Antibody-dependent cell cytotoxicity; T lymphocyte stimulants
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Orphan Drug Status
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity Yes
- Available For Licensing Yes
Highest Development Phases
- Phase I/II Neuroblastoma; Osteosarcoma; Small cell lung cancer; Solid tumours
- No development reported Ewing's sarcoma
Most Recent Events
- 08 Apr 2022 Y-mAbs Therapeutics terminates a phase I/II trial in Small cell lung cancer (Metastatic disease, Second-line therapy or greater, Recurrent) in USA due to business priorities (SC) (NCT04750239)
- 20 Oct 2021 Y-mAbs Therapeutics terminates phase I/II trial in Osteosarcoma (In adolescents, In adults, In children, In the elderly, Second-line therapy or greater) in USA (IV) (NCT03860207)
- 16 Aug 2021 Phase-I/II clinical trials in Small cell lung cancer (Metastatic disease, Second-line therapy or greater, Recurrent) in USA (SC) (NCT04750239)