AK 002

Drug Profile

AK 002

Alternative Names: AK002

Latest Information Update: 10 Jul 2018

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At a glance

  • Originator Johns Hopkins University School of Medicine
  • Developer Allakos
  • Class Anti-inflammatories; Antiallergics; Antibodies; Antifibrotics; Eye disorder therapies; Food allergy immunotherapies; Monoclonal antibodies; Skin disorder therapies
  • Mechanism of Action Immunomodulators; Mast cell inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Eosinophilic gastroenteritis; Urticaria
  • Phase I/II Peanut hypersensitivity
  • Phase I Conjunctivitis; Keratoconjunctivitis; Systemic mastocytosis
  • Preclinical Fibrosis

Most Recent Events

  • 02 Jun 2018 Preclinical data for Eosinophilic gastroenteritis presented at the Digestive Disease Week 2018 (DDW-2018)
  • 16 May 2018 Phase-I/II clinical trials in Peanut hypersensitivity in Denmark (IV) (EudraCT2018-000165-36)
  • 12 Apr 2018 Allakos plans a phase II ENIGMA trial for Eosinophilic Gastroenteritis in USA (NCT03496571)
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