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Ragifilimab - Agenus

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Drug Profile

Ragifilimab - Agenus

Alternative Names: AGEN-1876; Anti-GITR-agonist-antibody-Incyte; CM-701; INCAGN-01876; INCAGN-1876

Latest Information Update: 21 Jun 2023

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At a glance

  • Originator 4-Antibody; Ludwig Institute for Cancer Research
  • Developer Agenus; Incyte Corporation
  • Class Antineoplastics; Immunotherapies; Monoclonal antibodies
  • Mechanism of Action Antibody-dependent cell cytotoxicity; T lymphocyte stimulants; TNFRSF18 protein stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Squamous cell cancer
  • Discontinued Glioblastoma; Solid tumours

Most Recent Events

  • 21 Jun 2023 Phase-II clinical trials in Squamous cell cancer (Parenteral) (Agenus pipeline, June 2023)
  • 02 Jun 2023 Efficacy and adverse events data from a phase I/II trial in Solid tumours presented at the 59th Annual Meeting of the American Society of Clinical Oncology (ASCO-2023)
  • 02 Jun 2023 Efficacy and adverse events data from phase-II trial in Glioblastoma (Combination therapy, Neoadjuvant therapy, Recurrent) presented at the 59th Annual Meeting of the American Society of Clinical Oncology (ASCO-2023)

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