Either you have JavaScript disabled or your browser does not support Javascript . To work properly, this page requires JavaScript to be enabled.
How to enable JavaScript in your browser?

HLX 22

Next Previous
Drug Profile

HLX 22

Alternative Names: AC-101; HLX-22

Latest Information Update: 24 Dec 2025

Price :
$50 *
Note:
  • Adis is an information provider. We do not sell or distribute actual drugs.
  • Final gross price and currency may vary according to local VAT and billing address.
  • Your purchase entitles you to full access to the information contained in our drug profile at the time of purchase.
  • A link to download a PDF version of the drug profile will be included in your email receipt.

At a glance

  • Originator Alligator Bioscience
  • Developer Shanghai Henlius Biotech
  • Class Antineoplastics; Immunotherapies; Monoclonal antibodies
  • Mechanism of Action Antibody-dependent cell cytotoxicity; T lymphocyte stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Gastric cancer
  • New Molecular Entity Yes

Highest Development Phases

  • Phase III Adenocarcinoma
  • Phase II Breast cancer; Gastric cancer; HER2 positive breast cancer
  • No development reported Solid tumours

Most Recent Events

  • 09 Dec 2025 Shanghai Henlius Biotech plans a phase II/III trial for HER2 positive breast cancer (Combination therapy, Neoadjuvant therapy, Late-stage disease, First-line therapy) (Injection) in January 2026 (NCT07294534)
  • 09 Dec 2025 Shanghai Henlius Biotech plans a phase II/III trial for HER2-positive-breast-cancer (Combination therapy, First-line therapy, Recurrent, Metastatic disease, Late-stage disease) in January 2026 (NCT07294508)
  • 09 Dec 2025 NMPA approves IND applications for HLX 22 in combination with HLX 87 in HER 2 positive breast cancer

You need to be a logged in or subscribed to view this content

Request demo (opens in a new window)
If your organization or you do not have a subscription, try one of the following: If your organization has a subscription, there are several access options, even while working remotely:
  • Working within your organization’s network
  • with username/password or try to via your institution
  • Persisted access using your organization’s identifier stored in your user browser for 90 days
Back to top