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Drug Profile

Exaluren - Eloxx Pharmaceuticals

Alternative Names: ELX-02; NB-124; Synthetic aminoglycoside

Latest Information Update: 15 Nov 2024

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At a glance

Originator Technion - Israel Institute of Technology
Developer Eloxx Pharmaceuticals
Class Amines; Aminoglycosides; Antifibrotics; Small molecules
Mechanism of Action Ribosomal protein modulators

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

Yes - Cystinosis; Cystic fibrosis; Mucopolysaccharidosis I; Rett syndrome; Hereditary nephritis
New Molecular Entity Yes

Highest Development Phases

Phase II Cystinosis; Hereditary nephritis
Preclinical Cystic fibrosis
No development reported Duchenne muscular dystrophy; Mucopolysaccharidosis I; Rett syndrome

Most Recent Events

12 Nov 2024 Pharmacodynamics data from Phase-II trial in Hereditary nephritis released by Eloxx Pharmaceuticals
11 Jul 2024 Eloxx Pharmaceuticals completes pre-Investigational New Drug Application (PIND) meeting with the US FDA in USA to initiate a phase-II clinical trial for Hereditary nephritis
11 Jul 2024 Eloxx Pharmaceuticals plans to files an IND application with the US FDA in USA for Hereditary nephritis

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