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Doxorubicin liposomal - Taiwan Liposome Company

Drug Profile

Doxorubicin liposomal - Taiwan Liposome Company

Alternative Names: Doxolipad; Lipo-Dox; TLC 177

Latest Information Update: 31 Oct 2022

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At a glance

  • Originator Taiwan Liposome Company
  • Developer Chang Gung Memorial Hospital; Taiwan Liposome Company; TTY Biopharm
  • Class Anthracyclines; Antineoplastics; Antivirals; Cytostatic antibiotics; Doxorubicins; Hepatoprotectants; Small molecules
  • Mechanism of Action DNA intercalators; Reactive oxygen species stimulants; RNA synthesis inhibitors; Type II DNA topoisomerase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No

Highest Development Phases

  • Marketed Breast cancer; Kaposi's sarcoma; Ovarian cancer
  • Phase II HER2 negative breast cancer

Most Recent Events

  • 09 Sep 2022 Initial efficacy and adverse events data from a phase II trial in Breast cancer presented at the 47th European Society for Medical Oncology Congress (ESMO-2022)
  • 11 Mar 2021 No development reported - Phase-III for Ovarian cancer (Combination therapy, Late-stage disease, Metastatic disease, Second-line therapy or greater) in Taiwan, India (IV)
  • 29 May 2019 The Committee for Medicinal Products for Human Use (CHMP) confirms the adoption of negative opinion for MAA after re-examination for doxorubicin liposomal for Breast cancer and Ovarian cancer

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