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TLY 012

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Drug Profile

TLY 012

Alternative Names: TLY-012

Latest Information Update: 01 Apr 2025

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At a glance

  • Originator Theraly Fibrosis
  • Developer Johns Hopkins University School of Medicine; Theraly Fibrosis
  • Class Antifibrotics; Hepatoprotectants; Polyethylene glycols; Recombinant proteins
  • Mechanism of Action Immunosuppressants; TRAIL receptor 2 agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Systemic scleroderma; Pancreatitis
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Fibrosis; Liver cirrhosis; Pancreatitis; Systemic scleroderma

Most Recent Events

  • 01 Apr 2025 TLY 012 is still in phase I trials for Systemic-scleroderma, Pancreatitis, Liver-Cirrhosis, Fibrosis in USA (PO) (D&D Pharmatech pipeline, March 2025)
  • 28 Jan 2025 No recent reports of development identified for phase-I development in Fibrosis in USA (Parenteral)
  • 28 Jan 2025 No recent reports of development identified for phase-I development in Liver-Cirrhosis in USA (Parenteral)

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