Drug Profile
ZED 1227
Alternative Names: TAK-227; ZED-101; ZED-1227Latest Information Update: 09 Apr 2024
Price :
$50
*
At a glance
- Originator Zedira GmbH
- Developer Dr Falk Pharma; Takeda
- Class Hepatoprotectants; Imidazoles; Pyridines; Small molecules
- Mechanism of Action Transglutaminase 2 inhibitors
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Orphan Drug Status
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity Yes
Highest Development Phases
- Phase II Coeliac disease; Non-alcoholic fatty liver disease
Most Recent Events
- 31 Mar 2024 Phase-II clinical trials in Coeliac disease in Australia, Austria, Croatia, Finland, Georgia, Germany, New Zealand, Norway, Poland, Romania, Spain, Sweden, Switzerland and United Kingdom (PO) (ISRCTN79155276)
- 26 Jun 2023 Takeda completes a phase I trial in Coeliac diseases in USA (PO) (NCT05818956)
- 26 Jun 2023 Takeda completes a phase I pharmacokinetics trial (In volunteers, In adults) in USA (NCT05818956)