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JNJ 81201887

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Drug Profile

JNJ 81201887

Alternative Names: AAVCAGsCD59; HMR59; JNJ-1887; JNJ-81201887

Latest Information Update: 10 Oct 2023

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At a glance

  • Originator Tufts University
  • Developer Hemera Biosciences; Johnson & Johnson Innovative Medicine
  • Class Eye disorder therapies; Gene therapies; Recombinant proteins
  • Mechanism of Action Complement system protein inhibitors; Gene transference
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No

Highest Development Phases

  • Phase II Dry age-related macular degeneration
  • Phase I Wet age-related macular degeneration

Most Recent Events

  • 01 Oct 2023 Janssen Pharmaceuticals is now called Johnson & Johnson Innovative Medicine (Janssen Pharmaceuticals website, October 2023)
  • 06 Mar 2023 Phase-II clinical trials in Dry age-related macular degeneration (In the elderly, In adults) in USA (Intravitreous) (NCT05811351)
  • 13 Feb 2023 JNJ 81201887 is still in phase I trials for Dry age-related macular degeneration and Wet age-related macular degeneration in USA

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