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Research programme: aldosterone synthase inhibitors - ElexoPharm/Merck

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Drug Profile

Research programme: aldosterone synthase inhibitors - ElexoPharm/Merck

Alternative Names: Aldosterone synthase cytochrome P-450 inhibitors; CYP11B2 inhibitors - ElexoPharm; Cytochrome P-450 CYP11B2 inhibitors - ElexoPharm

Latest Information Update: 28 Sep 2025

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At a glance

  • Originator ElexoPharm GmbH
  • Developer ElexoPharm GmbH; Elicio Therapeutics; Merck & Co
  • Class Cardiovascular therapies
  • Mechanism of Action Cytochrome P-450 CYP11B2 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • No development reported Cardiovascular disorders; Fibrosis; Kidney disorders

Most Recent Events

  • 28 Sep 2025 No recent reports of development identified for preclinical development in Fibrosis in USA
  • 01 Jun 2023 Angion Biomedica has merged with Elicio Therapeutics to form Elicio Therapeutics
  • 16 May 2022 ANgion Biomedica plans to select a lead compound and initiate IND enabling studies for Fibrosis by 2022

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