Drug Profile

NT 157

Alternative Names: NT157

Latest Information Update: 07 Sep 2023

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At a glance

Originator Hebrew University of Jerusalem
Developer TyrNovo
Class Small molecules
Mechanism of Action Insulin receptor substrate protein inhibitors; STAT3 transcription factor inhibitors

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

No
New Molecular Entity Yes

Discontinued Colorectal cancer; Malignant melanoma; Osteosarcoma; Ovarian cancer; Precursor cell lymphoblastic leukaemia-lymphoma; Prostate cancer

07 Sep 2023 Discontinued - Preclinical for Colorectal cancer in Israel (IV)
07 Sep 2023 Discontinued - Preclinical for Malignant melanoma in Israel (IV)
07 Sep 2023 Discontinued - Preclinical for Ovarian cancer in Israel (IV)

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