Nangibotide - Inotrem

Drug Profile

Nangibotide - Inotrem

Alternative Names: CardioTREM; LR-12; Motrem

Latest Information Update: 17 Jul 2018

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At a glance

  • Originator Inotrem
  • Class Peptides
  • Mechanism of Action Immunomodulators; TREML1 protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Septic shock
  • Phase I Myocardial infarction

Most Recent Events

  • 17 Jul 2018 Phase-I clinical trials in Myocardial infarction in France (IV), before July 2018 (Inotrem pipeline, July 2018)
  • 13 Jun 2018 Inotrem completes a phase II trial in Septic shock in France, Belgium, Netherlands, Spain (IV) (NCT03158948) (EudraCT2016-005032-14)
  • 15 Nov 2017 LR 12 receives Priority Medicine (PRIME) status for Septic shock in European Union
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