Drug Profile

Orellanine

Alternative Names: ONC-175

Latest Information Update: 02 Apr 2025

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At a glance

Originator Sahlgrenska University Hospital
Developer Oncorena Holding
Class Antineoplastics; Biological toxins; Mycotoxins; Oxides; Pyridines; Small molecules
Mechanism of Action Undefined mechanism

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

No
New Molecular Entity Yes

18 Mar 2025 US FDA approves IND application for phase I/II Oncorella-1 trial for Renal cell carcinoma
03 Feb 2022 Phase-I/II clinical trials in Renal cancer (Late-stage disease, Metastatic disease) in Sweden (IV)
02 Mar 2021 Orellanine is still in preclinical trials for Renal cancer in Sweden

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