Leucine enkephalin - Virpax Pharmaceuticals
Alternative Names: Envelta™; Leucine enkephalin intranasal spray - Virpax Pharmaceuticals; METDoloron; Nanoenabled leucine5 enkephalin; NES-100; NM 0127; NM 127; PES200Latest Information Update: 28 Nov 2024
At a glance
- Originator Nanomerics
- Developer Nanomerics; National Center for Advancing Translational Sciences; University of Exeter; Virpax Pharmaceuticals
- Class Anxiolytics; Enkephalins; Essential amino acids; Opioid analgesics; Opioid peptides
- Mechanism of Action Opioid delta receptor agonists
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Orphan Drug Status
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity Yes
- Available For Licensing Yes - Pain
Highest Development Phases
- Preclinical Cancer pain; Pain; Post-traumatic stress disorders
- No development reported Neuropathic pain
Most Recent Events
- 21 Nov 2024 Virpax Pharmaceuticals and National Centre for Advancing Translational Sciences extends its research and development agreement for Leucine enkephalin intranasal spray in Pain
- 15 Nov 2023 Virpax Pharmaceuticals plans a phase-I trial in middle of 2024
- 18 Sep 2023 PES200 is still in preclinical trials for Post-traumatic stress disorders in Germany (Intranasal)