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Emrusolmin - Modag

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Drug Profile

Emrusolmin - Modag

Alternative Names: anle-138b; TEV-56286

Latest Information Update: 07 Oct 2025

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At a glance

  • Originator Ludwig-Maximilians-University; Max Planck Institute for Biophysical Chemistry
  • Developer Modag; Nottingham Trent University; Teva Pharmaceutical Industries
  • Class Antidementias; Antiparkinsonians; Dioxoles; Pyrazoles; Small molecules
  • Mechanism of Action Alpha-synuclein inhibitors; Protein aggregation inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Multiple system atrophy
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Multiple system atrophy
  • Phase I Unspecified
  • No development reported Alzheimer's disease; Creutzfeldt-Jakob disease; Parkinson's disease

Most Recent Events

  • 29 Sep 2025 Teva Pharmaceutical plans a phase II trial for Multiple system atrophy (PO) in USA in September 2025 (NCT07197866)
  • 09 Sep 2025 Emrusolmin - Modag receives Fast Track designation for Multiple system atrophy [PO,Capsule] in USA
  • 28 Jun 2025 No recent reports of development identified for phase-I development in Parkinson's-disease in United Kingdom (PO)

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