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OT 15

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Drug Profile

OT 15

Alternative Names: EE-TP; Erythrocyte Encapsulated Thymidine Phosphorylase; OT-15

Latest Information Update: 25 Oct 2023

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At a glance

  • Originator Orphan Technologies
  • Developer Orphan Technologies; St. Georges University of London; Travere Therapeutics
  • Class Enzymes
  • Mechanism of Action Enzyme replacements
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Metabolic disorders
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Mitochondrial myopathies

Most Recent Events

  • 20 Oct 2023 EryDel has been acquired and merged into Quince Therapeutics
  • 31 Jul 2023 St George's University of London in collaboration with Neovii Biotech withdrew the phase II TEETPIM trial in Mitochondrial myopathies (In adolescents, In adults, In the elderly) in United Kingdom (IV) due to change of circumstances with commercial partner (EudraCT2018-003000-39) (NCT03866954)
  • 25 Jul 2022 OT 15 is still in phase II trials for Mitochondrial myopathies (In adolescents, In adults, In the elderly) in United Kingdom (IV)

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