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OT 82

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Drug Profile

OT 82

Alternative Names: OT-82

Latest Information Update: 28 Jun 2025

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At a glance

  • Originator OncoTartis
  • Class Antineoplastics; Small molecules
  • Mechanism of Action Nicotinamide phosphoribosyltransferase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Preclinical Neuroblastoma
  • No development reported Haematological malignancies; Lymphoma

Most Recent Events

  • 28 Jun 2025 No recent reports of development identified for phase-I development in Lymphoma(Refractory metastatic disease, Second-line therapy or greater) in USA (PO, Suspension)
  • 11 Oct 2023 Preclinical trials in Neuroblastoma in USA (PO)
  • 11 Oct 2023 Pharmacodynamics data from a preclinical trial in Neuroblastoma presented at the AACR-NCI-EORTC Virtual International Conference on Molecular Targets and Cancer Therapeutics (AACR-NCI-EORTC -2023)

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