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Berdazimer sodium - SB 208 - Ligand Pharmaceuticals

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Drug Profile

Berdazimer sodium - SB 208 - Ligand Pharmaceuticals

Alternative Names: MAP3-NONOate - SB-208; NVN1000-SB208; SB-208

Latest Information Update: 25 Jun 2024

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At a glance

  • Originator University of North Carolina at Chapel Hill
  • Developer Ligand Pharmaceuticals; Novan Inc; Pelthos Therapeutics
  • Class Anti-inflammatories; Antiacnes; Antiandrogens; Antibacterials; Antifibrotics; Antifungals; Antihypertensives; Antipsoriatics; Antivirals; Esters; Free radicals; Macromolecular substances; Nitrogen oxides; Nitroso compounds; Non-opioid analgesics; Propylamines; Silicates; Silicon compounds; Skin disorder therapies; Vasodilators
  • Mechanism of Action Androgen receptor antagonists; Angiogenesis inducing agents; Cell death stimulants; Guanylate cyclase stimulants; Interleukin 13 inhibitors; Interleukin 4 inhibitors; Nitric oxide donors; NLRP3 protein inhibitors; Reactive oxygen species modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Tinea pedis
  • Suspended Onychomycosis

Most Recent Events

  • 25 Jun 2024 Phase-II clinical trials in Tinea pedis in Dominican Republic (Topical) prior to June 2024 (Pelthos Therapeutics pipeline, June 2024)
  • 27 Sep 2023 Ligand Pharmaceuticals acquires all the rights of all the assets related to the NITRICIL technology platform from Novan
  • 18 Feb 2022 Berdazimer sodium SB 208 is still in phase II trials for Tinea pedis in Dominican Republic (Novan pipeline, February 2022)

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