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Alpha-dihydrotetrabenazine

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Drug Profile

Alpha-dihydrotetrabenazine

Alternative Names: (+)-Alpha-Dihydrotetrabenazine; HTBZ

Latest Information Update: 30 Dec 2022

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At a glance

  • Originator Adeptio Pharmaceuticals
  • Developer Adeptio Pharmaceuticals; University of Michigan
  • Class Quinolizines; Small molecules
  • Mechanism of Action Dopamine receptor antagonists; Vesicular monoamine transporter 2 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No

Highest Development Phases

  • Phase II Tardive dyskinesia
  • No development reported Neurological disorders

Most Recent Events

  • 27 Dec 2022 Phase-II clinical trials in Tardive dyskinesia (In the elderly, In adults) in Czech Republic (PO) (EudraCT2022-001685-35)
  • 02 Sep 2022 Phase-II clinical trials in Tardive dyskinesia (In adults, In the elderly) in Croatia (PO) (EudraCT2022-000271-39)
  • 28 Aug 2019 No recent reports of development identified for phase-I development in Neurological-disorders(In volunteers) in USA (PO)

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