RC 48

Drug Profile

RC 48

Alternative Names: RC 48-ADC; RC-48

Latest Information Update: 25 Jun 2018

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At a glance

  • Originator Yantai Rongchang Biological Engineering
  • Class Antineoplastics; Drug conjugates; Immunoconjugates
  • Mechanism of Action Immunomodulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Breast cancer; Gastric cancer; Urogenital cancer
  • Phase I/II Solid tumours

Most Recent Events

  • 14 Jun 2018 Phase-II clinical trials in Gastric cancer (Late-stage disease, Metastatic disease, Second-line therapy or greater) in China (IV) (NCT03556345)
  • 01 Jun 2018 Interim efficacy and adverse events data from a phase I trial in Solid tumour presented at the 54th Annual Meeting of the American Society of Clinical Oncology(ASCO-2018)
  • 01 Jun 2018 Efficacy, adverse events and pharmacokinetic data from a phase Ib study in HER2-positive Metastatic breast cancer presented at the 54th Annual Meeting of the American Society of Clinical Oncology (ASCO-2018)
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