PAT 1251

Drug Profile

PAT 1251

Alternative Names: PAT-1251

Latest Information Update: 27 Nov 2017

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At a glance

  • Originator PharmAkea Therapeutics
  • Class Antifibrotics; Small molecules
  • Mechanism of Action LOXL2 protein-inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Idiopathic pulmonary fibrosis
  • Preclinical Hepatic fibrosis

Most Recent Events

  • 20 Oct 2017 Preclinical trials in Hepatic fibrosis in USA (PO)
  • 20 Oct 2017 Pharmacodynamics data from a preclinical trial in Hepatic fibrosis presented at the 68th Annual Meeting of the American Association for the Study of Liver Diseases (AASLD-2017)
  • 22 Aug 2017 PharmAkea completes the phase I trial in Idiopathic pulmonary fibrosis (In volunteers) in United Kingdom (PO)
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