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EQ 101

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Drug Profile

EQ 101

Alternative Names: BNZ-1; BNZ132-1; BNZ132-1-40; EQ-101

Latest Information Update: 14 Aug 2024

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At a glance

  • Originator Bioniz
  • Developer Bioniz; Equillium
  • Class Antineoplastics; Antivirals; Peptides; Skin disorder therapies
  • Mechanism of Action Interleukin 15 inhibitors; Interleukin 15 receptor antagonists; Interleukin 2 inhibitors; Interleukin 2 receptor antagonists; Interleukin 9 inhibitors; Interleukin 9 receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Cutaneous T-cell lymphoma
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II/III Cutaneous T-cell lymphoma
  • Phase II Alopecia areata; Large granular lymphocytic leukaemia; T-cell leukaemia
  • Research Vitiligo
  • No development reported Adult T-cell leukaemia-lymphoma; Tropical spastic paraparesis

Most Recent Events

  • 08 Aug 2024 Equillium plans a phase IIb trial for Alopecia areata in 2025 (SC)
  • 04 Jun 2024 Updated efficacy and adverse event data from a phase II trial in Alopecia areata released by Equillium
  • 30 Apr 2024 Equillium completes a phase II trial in Alopecia areata in Australia and New Zealand (IV) (NCT05589610)

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