Drug Profile


Alternative Names: BNZ-1; BNZ132-1; BNZ132-1-40

Latest Information Update: 01 Jun 2018

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At a glance

  • Originator Bioniz
  • Developer Bioniz; National Institutes of Health (USA)
  • Class Anti-inflammatories; Antineoplastics; Peptides
  • Mechanism of Action Immunomodulators; Interleukin 15 receptor antagonists; Interleukin 2 receptor antagonists; Interleukin 9 receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase I/II Cutaneous T cell lymphoma; T-cell leukaemia
  • Phase I Alopecia areata
  • Preclinical Adult T-cell leukaemia-lymphoma; Tropical spastic paraparesis

Most Recent Events

  • 04 Jun 2018 Bioniz Therapeutics plans a phase II trial for Alopecia Areata in October 2018 (NCT03532958)
  • 01 May 2018 Adverse events and pharmacodynamics data from a phase I trial in healthy volunteers released by Bioniz Therapeutics
  • 01 May 2018 Bioniz Therapeutics plans clinical trials for Alopecia areata
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