Cobolimab - AnaptysBio/GSK
Alternative Names: Anti-TIM-3-antibody-GSK; GSK-4069889; TSR 022; WBP 296ALatest Information Update: 27 Mar 2025
At a glance
- Originator AnaptysBio
- Developer AnaptysBio; GSK; TESARO; University of Pittsburgh
- Class Antineoplastics; Immunotherapies; Monoclonal antibodies
- Mechanism of Action Antibody-dependent cell cytotoxicity; HAVCR2 protein inhibitors; T lymphocyte stimulants
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Orphan Drug Status
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity Yes
Highest Development Phases
- Phase III Non-small cell lung cancer
- Phase II Cervical cancer; Liver cancer; Malignant melanoma
- Phase I/II Solid tumours
Most Recent Events
- 31 Dec 2024 AnaptysBio has patent protection for antibody sequence of Cobolimab and its variants, methods of use and related matters in multiple countries
- 31 Dec 2024 AnaptysBio has patents pending for Cobolimab in multiple countries
- 20 Dec 2024 Phase-I/II clinical trials in Solid tumours (Combination therapy, Late-stage disease, Metastatic disease, In neonates, In infants, In children, In adolescents, In adults) in USA (Parenteral) (NCT06521567)