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Research programme: HBV cccDNA formation inhibitors - Arbutus Biopharma

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Drug Profile

Research programme: HBV cccDNA formation inhibitors - Arbutus Biopharma

Alternative Names: ARB-199; ARB-596; cccDNA formation inhibitors - Arbutus; Covalently closed circular DNA formation inhibitors - Arbutus

Latest Information Update: 28 Mar 2018

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At a glance

  • Originator Baruch S. Blumberg Institute; Drexel University College of Medicine
  • Developer Arbutus Biopharma; Baruch S. Blumberg Institute
  • Class Antivirals; Small molecules
  • Mechanism of Action Hepatitis B virus replication inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • No development reported Hepatitis B

Most Recent Events

  • 28 Mar 2018 No recent reports of development identified for research development in Hepatitis-B in USA (PO)
  • 30 Aug 2016 Arbutus terminates its licence for VLP technology with Kuros
  • 19 Nov 2014 OnCore Biopharma and Baruch S Blumberg Institute enter into a research collaboration to develop treatments for Hepatitis B and Liver cancer

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