ACTR 087/rituximab combination therapy - Unum Therapeutics

Drug Profile

ACTR 087/rituximab combination therapy - Unum Therapeutics

Alternative Names: ACTR 087/rituximab combination therapy; ACTR087 + rituximab - Unum Therapeutics; ACTR087 + rituximab combination therapy; CD16V-41BB-CD3ζ; Viral ACTR + rituximab - Unum Therapeutics

Latest Information Update: 01 Feb 2018

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At a glance

  • Originator Unum Therapeutics
  • Class Antineoplastics; Gene therapies; Immunotherapies; Monoclonal antibodies; T lymphocyte cell therapies
  • Mechanism of Action B cell inhibitors; CD20 antigen inhibitors; Immunologic cytotoxicity; Immunostimulants; T lymphocyte replacements
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity No

Highest Development Phases

  • Phase I Non-Hodgkin's lymphoma

Most Recent Events

  • 01 Jan 2018 Phase-I clinical trials in Multiple myeloma (Combination therapy, Second-line therapy or greater) in USA (unspecified route) (NCT03266692)
  • 09 Dec 2017 Drug interactions, updated safety and efficacy data from a phase I trial in Non-Hodgkin's lymphoma presented at the 59th Annual Meeting and Exposition of the American Society of Hematology (ASH-2017)
  • 01 Nov 2017 Efficacy and adverse events data from a phase I trial in Non-Hodgkin's lymphoma released by Unum Therapeutics
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