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DNL 104

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Drug Profile

DNL 104

Alternative Names: DNL-104; DNLI-A-002

Latest Information Update: 27 Mar 2018

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At a glance

  • Originator Harvard University
  • Developer Denali Therapeutics Inc
  • Class Antidementias; Neuroprotectants; Small molecules
  • Mechanism of Action RIPK1 protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Neurodegenerative disorders

Most Recent Events

  • 27 Mar 2018 Discontinued - Phase-I for Neurodegenerative disorders in Netherlands (unspecified route)
  • 25 Aug 2016 Denali Therapeutics acquires Incro Pharmaceuticals
  • 25 Aug 2016 Denali Therapeutics plans a phase-I trial for Neurodegenerative disorders in Europe

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