Research programme: anti-cancer therapeutics - Ascentage Pharma

Drug Profile

Research programme: anti-cancer therapeutics - Ascentage Pharma

Alternative Names: APG 2449; APG 2575; APG-1022

Latest Information Update: 11 Jan 2017

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At a glance

  • Originator Ascentage Pharma
  • Class Antineoplastics; Small molecules
  • Mechanism of Action Anaplastic lymphoma kinase inhibitors; Apoptosis stimulants; Proto oncogene protein c met inhibitors; Proto oncogene protein c-akt inhibitors; Proto-oncogene protein c mdm2 inhibitors; Proto-oncogene protein c-bcl-2 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Preclinical Cancer

Most Recent Events

  • 27 May 2018 Ascentage Pharma Group plans a phase I trial of APG 2575 for Haematological-malignancies (PO) in June 2018 (NCT03537482)
  • 06 Nov 2017 Ascentage Pharma announces intention to submit IND to China FDA for APG 2449 for Non-small cell lung cancer in the first quarter 2018 (Ascentage Pharma pipeline, November 2017)
  • 10 Jan 2017 Research programme: anti-cancer therapeutics - Ascentage Pharma is available for licensing as of 10 Jan 2017.
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