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Vebreltinib - Apollomics/Beijing Pearl Biotechnology

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Drug Profile

Vebreltinib - Apollomics/Beijing Pearl Biotechnology

Alternative Names: APL-101; Bozitinib - Apollomics/Beijing Pearl Biotechnology; Bozitinib - Beijing Pearl Biotechnology/CBT Pharmaceuticals; CBI-3103; CBT-101; PLB-1001

Latest Information Update: 23 Sep 2024

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At a glance

  • Originator Crown Bioscience
  • Developer Apollomics; Beijing Pearl Biotechnology
  • Class Antineoplastics; Cyclopropanes; Fluorinated hydrocarbons; Indazoles; Pyrazoles; Pyridazines; Small molecules; Triazoles
  • Mechanism of Action Proto-oncogene protein c-met inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Non-small cell lung cancer
  • New Molecular Entity Yes
  • Available For Licensing Yes - Cancer

Highest Development Phases

  • Registered Glioblastoma; Non-small cell lung cancer
  • Phase II Solid tumours
  • Phase I/II Liver cancer; Renal cell carcinoma

Most Recent Events

  • 16 Sep 2024 Efficacy and adverse event data from a phase I/II trial in Non-small cell lung cancer released by Avistone Pharmaceuticals
  • 13 Aug 2024 Efficacy data from a phase I/II SPARTA trial in Solid tumours released by Apollomics
  • 05 Jun 2024 Updated adverse events data from the phase II KUNPENG trial in Non-small cell lung cancer released by Beijing Pearl Biotechnology

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