APL 102
Alternative Names: APL-102; CBT 102Latest Information Update: 29 Jul 2025
At a glance
- Originator CBT Pharmaceuticals
- Developer Apollomics
- Class Antineoplastics; Small molecules
- Mechanism of Action Angiogenesis inhibitors; Colony-stimulating factor receptor antagonists; Discoidin domain receptor 1 antagonists; Mitogen-activated protein kinase inhibitors; Platelet-derived growth factor receptor antagonists; Proto-oncogene protein b-raf inhibitors; Proto-oncogene protein c-ret inhibitors; Vascular endothelial growth factor receptor antagonists
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Orphan Drug Status
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity Yes
Highest Development Phases
- Phase I Solid tumours
Most Recent Events
- 29 Jul 2025 APL 102 is still in phase-I development in Solid-tumours(Inoperable/Unresectable, Late-stage disease, Metastatic disease, Second-line therapy or greater) in China (PO, Capsule)
- 28 Apr 2025 No recent reports of development identified for phase-I development in Solid-tumours(Inoperable/Unresectable, Late-stage disease, Metastatic disease, Second-line therapy or greater) in China (PO, Capsule)
- 03 Apr 2025 Apollomics terminates a phase-I clinical trial in Solid tumours (Late-stage disease, Inoperable/Unresectable, Metastatic disease, Second-line therapy or greater) in China (PO) due to adjustments in corporate development strategy (NCT05055518)