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Vibecotamab - Xencor

Drug Profile

Vibecotamab - Xencor

Alternative Names: CD123 x CD3 - Xencor; SQZ 622; XmAb 14045

Latest Information Update: 28 Dec 2021

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At a glance

  • Originator Xencor
  • Class Antineoplastics; Bispecific antibodies; Immunotherapies; Monoclonal antibodies
  • Mechanism of Action Antibody-dependent cell cytotoxicity; T lymphocyte stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Acute myeloid leukaemia

Most Recent Events

  • 28 Dec 2021 Phase I trial is still ongoing for Acute myeloid leukaemia (Second-line therapy or greater) in USA (NCT02730312)
  • 09 Nov 2021 Discontinued - Phase-I for Acute myeloid leukaemia (Second-line therapy or greater) in USA (IV)
  • 30 Sep 2021 Xencor completes a Phase-I trial in Acute myeloid leukemia (Second-line therapy or greater) in USA (IV) (NCT02730312)
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