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K1 70

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Drug Profile

K1 70

Alternative Names: K1-70™

Latest Information Update: 20 Feb 2026

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At a glance

  • Originator AV7
  • Class Eye disorder therapies; Monoclonal antibodies
  • Mechanism of Action Thyrotropin receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Graves ophthalmopathy
  • No development reported Graves' disease

Most Recent Events

  • 05 Feb 2026 Av7 plans a phase II trial for Graves ophthalmopathy and Graves' disease in Spain and Italy (IV, Infusion) (EudraCT2024-519292-26-00) (CTIS2024-519292-26-00)
  • 18 Dec 2025 No development reported - Phase-I for Graves' disease in Japan (IM)
  • 29 Apr 2025 Efficacy, adverse events and pharmacokinetics data from a phase I trial in Graves' disease released by AV7

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