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BMS 986207

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Drug Profile

BMS 986207

Alternative Names: Anti-TIGIT antibody - Bristol Myers Squibb; BMS-986207; ONO-4686

Latest Information Update: 18 Apr 2024

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At a glance

  • Originator Bristol-Myers Squibb
  • Developer Bristol-Myers Squibb; Compugen; Multiple Myeloma Research Consortium; Ono Pharmaceutical
  • Class Antineoplastics; Immunotherapies; Monoclonal antibodies
  • Mechanism of Action Antibody-dependent cell cytotoxicity; T lymphocyte stimulants; TIGIT protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Non-small cell lung cancer
  • Phase I/II Multiple myeloma; Solid tumours

Most Recent Events

  • 25 Jan 2024 Bristol-Myers Squibb completes a phase I/II trial in Solid tumours (Second-line therapy or greater, Combination therapy, Late-stage disease) in USA, Australia, Argentina, Canada, Chile, Japan, Romania and Singapore (Parenteral) (NCT02913313)
  • 25 Jan 2024 Bristol-Myers Squibb completes a phase I/II trial in Solid tumours (Second-line therapy or greater, Monotherpay, Late-stage disease) in USA, Australia, Argentina, Canada, Chile, Japan, Romania and Singapore (Parenteral) (NCT02913313)
  • 02 Jun 2023 Efficacy and adverse events data from a phase I/II trial in Solid tumours presented at the 59th Annual Meeting of the American Society of Clinical Oncology (ASCO-2023)
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