BMS 986207
Alternative Names: Anti-TIGIT antibody - Bristol Myers Squibb; BMS-986207; ONO-4686Latest Information Update: 26 Feb 2025
At a glance
- Originator Bristol-Myers Squibb
- Developer Bristol-Myers Squibb; Compugen; Multiple Myeloma Research Consortium; Ono Pharmaceutical
- Class Antineoplastics; Immunotherapies; Monoclonal antibodies
- Mechanism of Action Antibody-dependent cell cytotoxicity; T lymphocyte stimulants; TIGIT protein inhibitors
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Orphan Drug Status
No
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity Yes
Highest Development Phases
- Phase II Non-small cell lung cancer
- Phase I/II Multiple myeloma; Solid tumours
Most Recent Events
- 15 May 2024 Compugen completes phase-I/II clinical trials in Solid tumours (Combination therapy, Second-line therapy or greater, Late-stage disease) in USA (IV) (NCT04570839)
- 28 Apr 2024 No recent reports of development identified for preclinical development in Solid-tumours in USA (Parenteral)
- 25 Jan 2024 Bristol-Myers Squibb completes a phase I/II trial in Solid tumours (Second-line therapy or greater, Combination therapy, Late-stage disease) in USA, Australia, Argentina, Canada, Chile, Japan, Romania and Singapore (Parenteral) (NCT02913313)