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SI 001

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Drug Profile

SI 001

Alternative Names: Autologous stromal vascular fraction cells/oncolytic vaccinia virus; CAL1 vaccinia virus; CAL1 VV + autologous cell; SI-001; SVF+ACAM-200; SVF-CAL1; SVF/VV

Latest Information Update: 28 Dec 2021

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At a glance

  • Originator StemImmune
  • Developer Calidi Biotherapeutics
  • Class Antineoplastics; Immunotherapies; Oncolytic viruses; Stem cell therapies
  • Mechanism of Action Cell replacements; Immunologic cytotoxicity; Immunostimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No

Highest Development Phases

  • No development reported Solid tumours

Most Recent Events

  • 28 Dec 2021 No recent reports of development identified for phase-I development in Solid-tumours(Late-stage disease, Second-line therapy or greater) in USA (Parenteral)
  • 09 Oct 2019 Calidi Biotherapeutics plans to submit an Investigational New Drug (IND) application to the US FDA for phase Ib/II trials in Melanoma and Solid tumours
  • 09 Oct 2019 Calidi Biotherapeutics plans a phase Ib/IIa trial for Prostate cancer, Melanoma and other Solid tumours in USA

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