Sintilimab - Eli Lilly

Drug Profile

Sintilimab - Eli Lilly

Alternative Names: Anti-PD-1-antibody-Cinda; IBI-308; Sintilimab - Eli Lily/Innovent

Latest Information Update: 03 Jul 2018

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At a glance

  • Originator Innovent Biologics
  • Developer Cinda Biopharmaceutical; Eli Lilly; Innovent Biologics
  • Class Antineoplastics; Monoclonal antibodies
  • Mechanism of Action Immunomodulators; Programmed cell death-1 receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Preregistration Hodgkin's disease
  • Phase III Non-small cell lung cancer
  • Phase I Solid tumours
  • Discontinued Non-Hodgkin's lymphoma

Most Recent Events

  • 25 Jun 2018 Innovent Biologics plans a phase Ib trial for Solid malignancies (Late stage disease, Metastatic, IV) (NCT03568539)
  • 01 Jun 2018 Efficacy, adverse events and pharmacokinetic data from a phase I trial in advanced Solid tumours presented at the 54th Annual Meeting of the American Society of Clinical Oncology (ASCO-2018)
  • 01 Jun 2018 Efficacy and adverse events data from a phase II ORIENT I trial in Hodgkin's disease (Relapsed or refectory) presented at the 54th Annual Meeting of the American Society of Clinical Oncology (ASCO- 2018)
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