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PF 114

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Drug Profile

PF 114

Alternative Names: PF-114; PF-114 mesylate

Latest Information Update: 22 Feb 2022

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At a glance

  • Originator Fusion Pharma
  • Class Antineoplastics; Benzamides; Piperazines; Pyridines; Small molecules; Triazoles
  • Mechanism of Action Apoptosis stimulants; Bcr-Abl tyrosine kinase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I/II Chronic myeloid leukaemia

Most Recent Events

  • 11 Dec 2021 PF 114 is still in phase-I/II trials in Chronic myeloid leukaemia in Russia (PO)
  • 11 Dec 2021 Updated efficacy and adverse events data from a phase I/II trial in Chronic myeloid leukaemia presented at the 63rd American Society of Hematology Annual Meeting and Exposition(ASH-Hem-2021)
  • 07 Dec 2019 Interim efficacy and adverse events data from a phase I/II trial in Chronic myeloid leukaemia presented at the 60th Annual Meeting and Exposition of the American Society of Haematology (ASH-Hem-2019)

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