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Aflibercept sustained release - Regeneron/Ocular Therapeutix

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Drug Profile

Aflibercept sustained release - Regeneron/Ocular Therapeutix

Alternative Names: Aflibercept punctal plug - Regeneron/Ocular Therapeutix; Aflibercept suprachoroidal injection - Regeneron/Ocular Therapeutix; anti-VEGF antibody implant; OTX IVT; OTX-AFS

Latest Information Update: 21 Nov 2021

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At a glance

  • Originator Ocular Therapeutix; Regeneron Pharmaceuticals
  • Class Antineoplastics; Eye disorder therapies; Immunoglobulin Fc fragments; Immunoglobulin fragments; Recombinant fusion proteins
  • Mechanism of Action Placenta growth factor inhibitors; Vascular endothelial growth factor A inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No

Highest Development Phases

  • Discontinued Diabetic macular oedema; Retinal vein occlusion; Wet age-related macular degeneration

Most Recent Events

  • 05 Aug 2021 regeneron Pharmaceuticals terminates its option and license agreement collaboration with Ocular Therapeutix for Aflibercept sustained release
  • 05 Aug 2021 Discontinued - Preclinical for Diabetic macular oedema in USA (Intravitreous)
  • 05 Aug 2021 Discontinued - Preclinical for Retinal vein occlusion in USA (Intravitreous)

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