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Bomedemstat - Imago BioSciences

Drug Profile

Bomedemstat - Imago BioSciences

Alternative Names: Bomedemstat tosylate - Imago BioSciences; IMG-241 bis-tosylate salt; IMG-7289; LSD1 inhibitor - Imago BioSciences

Latest Information Update: 14 Jun 2022

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At a glance

  • Originator Imago BioSciences
  • Class Amides; Amines; Antihaemorrhagics; Antineoplastics; Benzamides; Benzene derivatives; Cyclopropanes; Fluorobenzenes; Piperazines; Small molecules; Triazoles
  • Mechanism of Action Lysine specific demethylase 1 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Myelofibrosis; Essential thrombocythaemia; Acute myeloid leukaemia
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Acute myeloid leukaemia; Essential thrombocythaemia; Myelodysplastic syndromes; Myelofibrosis; Polycythaemia vera
  • Phase I/II Small cell lung cancer

Most Recent Events

  • 10 Jun 2022 Interim efficacy and adverse events data from a phase II trial in essential thrombocythemia released by Imago BioSciences
  • 10 Jun 2022 Updated efficacy and adverse events data from a phase II trial in Myelofibrosis presented at 30th European Hematology Association Annual Meeting and Congress (EHA-2022)
  • 12 May 2022 Imago BioSciences announces intention to submit regulatory approvals to FDA and EMA for Essential thrombocythaemia
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