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Botulinum toxin E - AbbVie

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Drug Profile

Botulinum toxin E - AbbVie

Alternative Names: AGN 151586; BoNT/E; BoNTE; EB-001; EB-001A; EB-001T

Latest Information Update: 19 Apr 2024

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At a glance

  • Originator Bonti
  • Developer AbbVie
  • Class Antispasmodics; Bacterial proteins; Bacterial toxins; Botulinum toxins; Muscle relaxants; Recombinant proteins; Skin disorder therapies
  • Mechanism of Action Acetylcholine inhibitors; Glutamate antagonists; Neuromuscular blocking agents; SNARE protein antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase III Glabellar lines
  • Discontinued Musculoskeletal pain; Scars

Most Recent Events

  • 19 Apr 2024 Discontinued - Phase-II for Musculoskeletal pain in USA (IM) before April 2024 (Abbvie pipeline, April 2024)
  • 19 Apr 2024 Discontinued - Phase-II for Scars in USA (IM) before April 2024 (Abbvie pipeline, April 2024)
  • 03 Apr 2024 AbbVie completes a phase I/II trial in Glabellar lines in Japan (IM) (NCT06151561)

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