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SAR 440340

Drug Profile

SAR 440340

Alternative Names: REGN-3500; SAR440340

Latest Information Update: 28 Aug 2020

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At a glance

  • Originator Regeneron Pharmaceuticals; Sanofi
  • Class Anti-inflammatories; Antiasthmatics; Monoclonal antibodies; Skin disorder therapies
  • Mechanism of Action Interleukin-33 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Asthma; Chronic obstructive pulmonary disease
  • No development reported Allergic asthma; Inflammation
  • Discontinued Atopic dermatitis

Most Recent Events

  • 28 Aug 2020 No recent reports of development identified for phase-I development in Allergic-asthma(Monotherapy) in United Kingdom (IV)
  • 28 Aug 2020 No recent reports of development identified for phase-I development in Allergic-asthma(Monotherapy) in USA (IV)
  • 24 Jul 2020 Regeneron Pharmaceuticals and Sanofi completes a phase II trial in Atopic dermatitis (Monotherapy) in United Kingdom, Poland, South Korea, Japan, Hungary, Canada, Czech Republic, Australia and the US (SC) (EudraCT2018-001544-64) (NCT03738423)
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