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RVT 2001

Drug Profile

RVT 2001

Alternative Names: H3B-8800; RVT-2001

Latest Information Update: 27 Feb 2025

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At a glance

  • Originator H3 Biomedicine
  • Developer Eisai Inc; H3 Biomedicine
  • Class Antineoplastics; Small molecules
  • Mechanism of Action SF3B1 protein modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Acute myeloid leukaemia; Chronic myelomonocytic leukaemia
  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Acute myeloid leukaemia; Chronic myelomonocytic leukaemia; Myelodysplastic syndromes

Most Recent Events

  • 07 Dec 2024 Pharmacodynamics data from preclinical study presented at the 66th American Society of Hematology Annual Meeting and Exposition (ASH-Hem-2024)
  • 13 Feb 2024 Discontinued - Phase-I for Acute myeloid leukaemia in Taiwan, South Korea, Italy, Belgium, Germany, Spain, France, USA (PO)
  • 13 Feb 2024 Discontinued - Phase-I for Chronic myelomonocytic leukaemia in Taiwan, South Korea, Italy, Belgium, Germany, Spain, USA, France (PO)

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