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Calcium/magnesium/potassium/sodium oxybates - Jazz Pharmaceuticals

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Drug Profile

Calcium/magnesium/potassium/sodium oxybates - Jazz Pharmaceuticals

Alternative Names: Calcium, magnesium, potassium, and sodium oxybates oral solution; JZP-258; Lower sodium oxybate; LXB; Oxybate mixed salt solution – Jazz Pharmaceuticals; Xywav

Latest Information Update: 12 Jun 2024

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At a glance

  • Originator Jazz Pharmaceuticals plc
  • Class Hydroxybutyrates; Sleep disorder therapies; Small molecules
  • Mechanism of Action Dopamine receptor agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Idiopathic hypersomnia; Narcolepsy
  • New Molecular Entity No

Highest Development Phases

  • Marketed Cataplexy; Idiopathic hypersomnia; Narcolepsy

Most Recent Events

  • 13 Apr 2024 Efficacy data from a phase III trial in Idiopathic hypersomnia presented at the 76th Annual Meeting of the American Academy of Neurology 2024 (AAN-2024)
  • 10 Sep 2023 Adverse events and pharmacokinetics data from a phase-I trial in healthy volunteers presented at the American College of Clinical Pharmacology (ACCP-2023)
  • 22 Apr 2023 Long term adverse events data from a phase III trial in Narcolepsy with Cataplexy presented at the 75th Annual Meeting of the American Academy of Neurology 2023 (AAN-2023)

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