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Lorundrostat - Mineralys Therapeutics

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Drug Profile

Lorundrostat - Mineralys Therapeutics

Alternative Names: MLS-101; MT-4129

Latest Information Update: 28 Jan 2025

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At a glance

  • Originator Mitsubishi Tanabe Pharma Corporation
  • Developer Mineralys Therapeutics; Mitsubishi Tanabe Pharma Corporation
  • Class Acetamides; Amides; Antihypertensives; Benzene derivatives; Cardiovascular therapies; Cyclohexylamines; Small molecules; Triazines
  • Mechanism of Action Aldosterone synthase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase III Hypertension
  • Phase II Renal failure
  • No development reported Cardiovascular disorders

Most Recent Events

  • 08 Jan 2025 Mineralys Therapeutics plans a phase II trial for Sleep apnoea syndrome and Hypertension in USA (PO), (NCT06785454),
  • 08 Jan 2025 US FDA approves IND application for Lorundrostat in Sleep apnoea syndrome and Hypertension
  • 30 Oct 2024 Mineralys Therapeutics completes enrollment in phase III trials in Hypertension (Adjunctive treatment) in USA, Australia, Bulgaria, Canada, France, Germany, Italy, Netherlands, Poland, Puerto Rico, Spain, Romania, UK (PO)

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