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Lorundrostat - Mineralys Therapeutics

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Drug Profile

Lorundrostat - Mineralys Therapeutics

Alternative Names: MLS-101; MT-4129

Latest Information Update: 10 Apr 2025

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At a glance

  • Originator Mitsubishi Tanabe Pharma Corporation
  • Developer Mineralys Therapeutics; Mitsubishi Tanabe Pharma Corporation
  • Class Acetamides; Amides; Antihypertensives; Benzene derivatives; Cardiovascular therapies; Cyclohexylamines; Small molecules; Triazines; Urologics
  • Mechanism of Action Aldosterone synthase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase III Hypertension
  • Phase II Renal failure
  • No development reported Cardiovascular disorders

Most Recent Events

  • 29 Mar 2025 Adverse events and efficacy data from a phase II ADVANCE-HTN trial in Hypertension released by Mineralys Therapeutics
  • 10 Mar 2025 Adverse events and efficacy data from a phase II ADVANCE-HTN trial in Hypertension released by Mineralys Therapeutics
  • 10 Mar 2025 Adverse events and efficacy data from a phase II LAUNCH-HTN trial in Hypertension released by Mineralys Therapeutics

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