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Mazdutide - Eli Lilly and Company

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Drug Profile

Mazdutide - Eli Lilly and Company

Alternative Names: IBI-362; LY-3305677; OXM-3

Latest Information Update: 23 Sep 2025

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At a glance

  • Originator Eli Lilly and Company
  • Developer Eli Lilly and Company; Innovent Biologics
  • Class Antihyperglycaemics; Gastrointestinal hormones; Heart failure therapies; Hepatoprotectants; Obesity therapies; Peptides; Uricosurics
  • Mechanism of Action Glucagon receptor agonists; Glucagon-like peptide-1 receptor agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Obesity
  • Registered Type 2 diabetes mellitus
  • Phase III Non-alcoholic fatty liver disease; Sleep apnoea syndrome
  • Phase II Alcoholism; Heart failure; Non-alcoholic steatohepatitis
  • Phase I/II Polycystic ovary syndrome
  • Preclinical Hyperuricaemia

Most Recent Events

  • 19 Sep 2025 Registered for Type 2 diabetes mellitus in China (SC)
  • 03 Aug 2025 Launched for Obesity in China (SC) (Prior to August 2025) (Innovent Biologics pipeline, August 2025)
  • 09 Jul 2025 Eli Lilly and Company completes phase-II clinical trials in Obesity in USA (SC) (NCT06124807)

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