Mazdutide - Eli Lilly and Company
Alternative Names: IBI-362; LY-3305677; OXM-3Latest Information Update: 04 Nov 2025
At a glance
- Originator Eli Lilly and Company
- Developer Eli Lilly and Company; Innovent Biologics
- Class Antihyperglycaemics; Gastrointestinal hormones; Heart failure therapies; Hepatoprotectants; Obesity therapies; Peptides; Sleep disorder therapies; Uricosurics
- Mechanism of Action Glucagon receptor agonists; Glucagon-like peptide-1 receptor agonists
-
Orphan Drug Status
No
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity Yes
Highest Development Phases
- Marketed Obesity
- Registered Type 2 diabetes mellitus
- Phase III Non-alcoholic fatty liver disease; Sleep apnoea syndrome
- Phase II Alcoholism; Heart failure; Non-alcoholic steatohepatitis
- Phase I/II Polycystic ovary syndrome
- Preclinical Hyperuricaemia
Most Recent Events
- 26 Oct 2025 Adverse events and efficacy data from the phase III DREAMS-3 trial in Type 2 diabetes mellitus and Obesity released by Innovent Biologics
- 19 Sep 2025 Registered for Type 2 diabetes mellitus in China (SC)
- 03 Aug 2025 Launched for Obesity in China (SC) (Prior to August 2025) (Innovent Biologics pipeline, August 2025)