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RBX 7455

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Drug Profile

RBX 7455

Alternative Names: Microbiota Restoration Therapy - Ferrings Pharmaceuticals; RBX-7455

Latest Information Update: 18 Feb 2026

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At a glance

  • Originator Rebiotix
  • Developer Ferring Pharmaceuticals; Mayo Clinic; Rebiotix
  • Class Antibacterials; Antineoplastics; Bacteria
  • Mechanism of Action Bacteria replacements; Gastrointestinal microbiome modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Hepatic encephalopathy
  • No development reported Breast cancer; Clostridium difficile infections

Most Recent Events

  • 18 Feb 2026 No development reported - Phase-I for Clostridium difficile infections (Prevention) in USA (PO)
  • 28 Oct 2023 No recent reports of development identified for phase-I development in Breast-cancer in USA (PO, Capsule)
  • 13 Oct 2023 Rebiotix terminates a phase II trial for Hepatic Encephalopathy in the US (PO, Capsules), since the company was unable to recruit participants (NCT04155099)

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