XMT 1522

Drug Profile

XMT 1522

Alternative Names: TAK 522; XMT1522

Latest Information Update: 23 Jul 2018

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At a glance

  • Originator Adimab; Mersana Therapeutics
  • Developer Mersana Therapeutics; Takeda
  • Class Antineoplastics; Auristatins; Immunoconjugates; Immunotoxins
  • Mechanism of Action Immunomodulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Breast cancer; Gastric cancer; Non-small cell lung cancer

Most Recent Events

  • 19 Jul 2018 The US FDA places partial clinical hold on phase I trial of XMT 1522
  • 04 Jun 2018 Interim efficacy, pharmacodyamics and adverse events data from a phase I trial in Breast cancer and Gastric cancer presented at the Annual Meeting of the American Society of Clinical Oncology (ASCO-2018)
  • 14 May 2018 Mersana Therapeutics has patent protection in USA and foreign countries across its platforms and programmes
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